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We often think of bacteria in the context of dangerous or annoying infections. However, bacteria themselves can be infected by even smaller and more abundant entities: viruses called bacteriophages. This First-Year Seminar will combine readings and discussion of the fundamental biology of phages and their role in controlling populations of bacteria, with lab work to discover new phages from the Johns Hopkins campus. Phages identified in this class will be added to the Science Education Alliance’s archive which is comprised of phages from over 100 academic institutions worldwide and is a resource for phage biologists and physicians directly involved in developing phages as a treatment for disease.