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From capturing the intricate structure of a single atom to unveiling the grandeur of distant galaxies, the science of imaging bridges the smallest and largest scales of the universe. This First-Year Seminar delves into the fascinating interplay between technology, physics, and visualization, exploring how images are created, analyzed, and applied in groundbreaking scientific research. We'll examine the principles behind diverse imaging techniques: medical imaging tools like MRI and CT scans that save lives, telescopes that peer into the cosmos, and electron microscopes that reveal the building blocks of matter. Alongside the technical insights, we'll discuss the scientific stories these images tell--how they've shaped discoveries in fields like astrophysics, molecular biology, and quantum mechanics.