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Up-to-date primary literature manuscripts related to new discoveries and new strategies that are allowing scientists to make amazing progress in biomedical research will be presented. Examples include: labeling neurons with up to 90 different colors to trace their circuitry, evolution studies in glowing bacteria, detecting several viruses on a single chip and using fiber optics and channel rhodopsin to induce sleep. Students should be interested in reading primary literature research papers and discussing them in class.