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This is a natural products chemistry course organized according to the major natural product groups and emphasizing their origins, fundamental chemistry and applications in medicine. The organization is part traditional lecture and part case studies, like law school or business school, involving your participation in independent research, short essays and presentations. The last Workshops will be elective on your part as to topic with approval from C.A.T. Mixed in will be examples of organic and chemoenzymatic synthesis and biomimetic synthesis, relevant aspects of cofactor and enzyme function and their engineering, spectroscopic and kinetic tools.