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In the forty years since laboratories were first treated as ethnographic field sites, the core questions guiding anthropology and science and technology studies (STS) have grown increasingly intertwined. How does knowledge get made, and how does it come to matter? How do the objects of technoscience become embedded in everyday practice and in our senses of self, and how do shared imaginaries influence the kinds of futures technologists strive to produce? This course will explore critical moments in the development of STS through texts that blur the lines between experts and kin in biomedicine, finance, industrial agriculture, drone warfare, transnational surrogacy, and other technoscientific spaces.