3.0

credits

Average Course Rating

What is the first molecule of life? RNA embodies both informational and catalytic function, making it an ideal candidate for the first genetic biomolecule. In this course, we will explore the RNA world hypothesis by introducing different RNA molecules and discussing their functions. Students will learn the history of RNA biology discoveries through current topics in the field, such as RNA interference and CRISPR. Also, we will discuss the roles of essential cellular RNA-protein complexes, such as the ribosome and spliceosome. By the end of the class, students will have a general understanding of RNA biology and be familiar with RNA biotechnology techniques. Students will also gain experience reading scientific literature to learn advances in the field, discuss current applications, ethics and social impact of RNA biotechnology. Students’ performance will be evaluated by short written essays and student-led seminars on promising new directions for the field. Recommended Course Background: (AS.250.135 or AS.020.305) or equivalent knowledge of molecular biology.