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The Germ Theory in Literature is a writing course for science and public health majors, and for writing majors interested in science and public health. We examine the use of germs in popular literature, from 1900 to the present (with works by Paul de Kruif, Sinclair Lewis, Milton Silverman, Berton Roueché, Richard Preston, Laurie Garrett and John Barry). Students examine what happens to science when it is popularized in mainstream literature, and learn to write essays and opinion pieces using crisp, clear and purposeful prose. This course includes a writing workshop.