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This course covers physical, chemical, radiation, and biological hazards typically found in Johns Hopkins University research laboratories. It will use the “RAMP” (Recognize, Assess, Minimize, Prepare) framework originating in (Hill, R.H. Finster, D.C. Laboratory Safety For Chemistry Students, Wiley, 2nd Edition, 2016, 576pp.) and adopted by the American Chemical Society as a core concept for teaching laboratory safety. This framework does not depend on chemistry-specific practices (although it encompasses them as well as other disciplines), so it transfers well to general university-level research. The course also discusses the concepts of Inherently Safer Design of experiments. The course begins with a RAMP analysis of an assigned paper from the literature and concludes with a project analyzing a paper of the student’s choice.