Semester.ly

Johns Hopkins University | EN.510.426

Misfolding Diseases and the Thermodynamics of Protein Folding

3.0

credits

Average Course Rating

(4.42)

This class is an overview of protein structure, folding, and interactions, with emphasis of protein misfolding and human disease. Topics include the hydrophobic effect, self assembly, thermodynamics of protein folding, kinetics of protein folding, and protein association. Special emphasis is placed on experimental techniques, including peptide synthesis, peptide separation and purification techniques, UV-vis, CD, fluorescence, calorimetry, mass-spec, etc. Co-listed with EN.510.621

Fall 2012

(4.5)

Fall 2013

(4.44)

Fall 2014

(4.31)

Fall 2012

Professor: Kalina Hristova

(4.5)

The best aspect of this course was the student presentations of different research techniques. The worst aspect of this course was the dul lectures. Each student had to do a one hour presentation, which made it often difficult for the other students to pay attention in class. The course would improve if the length 196 of the class presentations were cut short and perhaps divided into two different presentations. Prospective students should know that this worthwhile course wil teach students a lot about research.

Fall 2013

Professor: Kalina Hristova

(4.44)

Students thought that the lectures were the best aspect of this course, because the information was interesting and well-explained. Students did not like the student lectures and believed that more guest lecturers would have been more beneficial. Students also wanted some hands-on experiences throughout the course. Prospective students should be prepared for a fair amount of reading and writing, but know that it is an enjoyable class with interesting materials.

Fall 2014

Professor: Kalina Hristova

(4.31)

Students praised this course for covering a variety of basic ideas that allowed students to better understand techniques and research in the bioengineering field. Student had mixed views on the course’s lectures. Multiple students thought topics were covered so quickly that if students didn’t pay attention and take good notes it was easy to miss key topics and feel lost. Suggestions for improvement largely centered on a desire that the course be better structured. Some students wanted the instructor to provide students with copies of her PowerPoint slides and a lecture recording so that students could review material outside of the classroom. Prospective students should know that students found that a good understanding of thermodynamics, kinetics and biology was helpful when taking this course. Overal students felt that the course had a reasonable workload and covered interesting topics.

Lecture Sections

(01)

No location info
K. Hristova
13:30 - 14:45