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Johns Hopkins University | EN.580.444

Biomedical Applications of Glycoengineering

3.0

credits

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(-1)

This course provides an overview of carbohydrate-based technologies in biotechnology and medicine. The course will begin by briefly covering basics of glycobiology and glycochemistry followed by detailed illustrative examples of biomedical applications of glycoengineering. A sample of these applications include the role of sugars in preventative medicine (e.g., for vaccine development and probiotics), tissue engineering (e.g., exploiting natural and engineered polysaccharides for creating tissue or organs de novo in the laboratory), regenerative medicine (e.g., for the treatment of arthritis or degenerative muscle disease), and therapy (e.g., cancer treatment). A major part of the course grade will be based on class participation with each student expected to provide a “journal club” presentation of a relevant paper as well as participate in a team-based project designed to address a current unmet clinical need that could be fulfilled through a glycoengineering approach. Recommended Course Background: EN.580.221 Molecules and Cells.

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