3.0

Average Course Rating

This course focuses on the application of engineering fundamentals to design cell/tissue-based systems for modulating immune response in treating disease. Concepts of immune cell development, surveillance, migration, and activation/inhibition will be introduced. Students will learn tissues in the body important for trafficking of immune players to local sites of therapeutic response. Engineering concepts required to alter immune cell or tissue function will be explored. Emphasis will be placed on synthetic biology methods such as viral or CRISPR-based techniques as well as necessary (pre/post) isolation and adoptive transfer techniques. In addition, animal models and various in vivo as well as ex vivo toolsets often used in the world of Immunology will be discussed.