2.0

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Average Course Rating

This is a seminar-style course focused on cutting edge molecular, cellular, mathematical, and computational biology of mammalian epigenetics and epigenomics in relationship to environmental exposure and human disease. The four main topics of the course are: epigenetics and DNA methylation; gene-environmental interaction and its relationship to epigenetics; cancer epigenetics; potential energy landscapes for epigenetic analysis. The format is a Socratic-style seminar with three alternating components: (1) “Big Ideas” focused on general principles presented by the instructor and questions from the students; (2) “Methods Development” focused on the logic behind current laboratory and computational methods; and (3) “Current Literature” focused on how to extract believable information from current journal articles. There are also four computational lab projects. Recommended Background: Laboratory course in organic chemistry, biochemistry, or cell biology; introductory statistics; familiarity with R, Python, or MATLAB