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Theoretical methods for analyzing information encoding and functional representations in neural systems. Models of single and multiple neural spike trains based on stochastic processes and information theory; detection and estimation of behaviorally relevant parameters from spike trans; system theoretic methods for analyzing sensory receptive fields; network models of neural systems. Both theoretical methods and the properties of specific well-studied neural systems will be discussed. Recommended Course Background: EN.580.422 or equivalent, EN.550.420 or equivalent, EN.580.222 or equivalent.