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This course will provide an in-depth exploration of the design and conduct of research in the health sciences. Students will evaluate common quantitative research designs, sources of bias and how to minimize bias in all steps of the research process across designs, and assess major concepts and principles relevant to research design and analytical approaches. Students will learn the strengths and weaknesses as well as when and how to use these designs and methods by studying and critiquing relevant examples from the literature and ongoing research by faculty. Special issues in the analysis and interpretation of data from various research designs and the critical evaluation of measurement techniques will be addressed. Discussions will also cover the ways in which the nursing perspective shapes the conduct and results of research.