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Provides an introduction to neuroimaging methods, relevance and possible implementations of these methods and background to critically evaluate neuroimaging applications in mental and behavioral health research. Introduces basic principles of neuroimaging as applied to human subjects research and specifically public health research. Reviews various imaging applications in the context of their specific methods, source of signal, goals and limitations, and research design and statistics and relevance to mental and behavioral health. Encourages critical evaluation of neuroimaging methods in public mental and behavioral health through review of published studies.