2.0

credits

Average Course Rating

Introduces students to a general framework for the assessment of comparative effectiveness and safety research. The framework, which can be applied to both observational data and randomized trials with imperfect adherence to the protocol, relies on the specification of a (hypothetical) target trial. Explores key challenges for comparative effectiveness research and critically reviews methods proposed to overcome those challenges. The methods are presented in the context of several case studies for cancer, cardiovascular, renal, and infectious diseases.