3.0

Average Course Rating

Offers the second of a three-part series of graduate courses in Genetic Epidemiology. Details the concepts of linkage disequilibrium and population genetics, including methods for admixture analysis useful for adjusting for individual variation in genetic ancestry/background. Presents the principles of genetic association analyses for quantitative and qualitative phenotypes for population-based studies. Details the concepts and tools related to confounding due to population stratification, and approaches for genome-wide association and epigenome association studies. Introduces concepts for linkage analysis in families and use of high-throughput sequence data (whole exome and whole genome). Dedicates selected class sessions to computer labs to illustrate the methods covered.