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Being a successful professional involves providing reliable answers to practical questions. Obtaining reliable answers benefits from two components. First, one needs a theoretical framework used to organize the data. Second, one needs a suitable statistical method to summarize the implications and properties of the data to develop an intelligible answer to the question at hand. Unfortunately, there is no “cookbook” available that could turn an amateur into a successful professional. Hence this course prepares students to develop the habit of asking the two important questions for professional life: How do you know and what is the alternative? A successful applied research project integrates these two questions into providing reliable answers.