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Sanctions and similar forms of economic coercion have become measures of first resort for policymakers around the world. But the effects of sanctions on targeted states and societies remain little studied and poorly understood. This course examines the effects of sanctions at multiple levels of analysis, using frameworks from political science, economics, sociology, and anthropology alongside empirical evidence from a wide range of recent sanctions cases, including Afghanistan, Iran, Russia, Syria, and Venezuela. In the first half of the course, students explore how sanctions effect economic systems, sectors, firms, households, and, ultimately, individuals. In the second half of the course, students examine the political and social effects of economic coercion, building up from the individual to the body politic. Alongside weekly lectures, a portion of class time is devoted to a collaborative research project in which the class conducts its own assessment of sanctions effects using a case study approach. In this way, the course equips students with the theoretical and practical insights needed to account for sanctions effects when setting strategies or policies, whether in government, the private sector, or non-governmental organizations. This course will also empower students who wish to advocate for those harmed by the unintended effects of sanctions.