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This course reviews the most important challenges that the technological revolution is bringing to the international recognition and protection of human rights. The students will differentiate the kind of challenges deriving from the digital space as well as those created by developments in the biotechnology revolution and will reflect on instruments and potential interventions at the global or national levels that can help the world move into the technological revolution while safeguarding one the most important legacies of the 20th Century: the creation of an international ethos on the protection of human rights, consolidated as a universal aspiration.